Director Jason Reitman has already made films about an adult woman clinging to her teens (Young Adult) and pregnancy (Juno). In his upcoming film Tully, he tackles a new stage of growing up: motherhood.

Charlize Theron stars as Marlo, an overwhelmed expectant mother of soon-to-be three, who is gifted with a night nurse by her brother (Mark Duplass). Wary at first, Marlo comes to form a unique bond with Tully (Mackenzie Davis).

The trailer begins with shots of Marlo asleep on a couch as her children play around her, and continues into a montage of small frustrations, like the bag containing her pumped breast milk falling over in the middle of the night, and Marlo dropping her phone on her infant’s face.Though she’s initially hesitant to invite a “night nanny” into her home, Tully (Mackenzie Davis) provides a necessary sounding board and emotional support.

“Mom, what’s wrong with your body?” her son asks after Marlo, pregnant, takes off her shirt when he spills a drink on it during dinner.

WATCH: Here’s the full trailer of Tully

“I hold a baby all day and then nighttime rolls around and I’m supposed to just switch gears like, ‘Hello, all sexy now,'” Theron says in voiceover. “Your twenties are great. But then your thirties come around the corner like a garbage truck at 5 a.m.”

“I’m here to help you with everything,” Tully explains. “You can’t fix the parts without treating the whole.”

“You’re convinced that you’re this failure, but you actually made your biggest dream come true,” Davis counters in another moment.

Tully marks Reitman and screenwriter Diablo Cody’s third collaboration (they previously worked together on Juno and Young Adult) and the second time that Theron and Reitman have worked together (they previously collaborated on Young Adult).

The film also stars Ron Livingston as Drew, Marlo’s husband.

Focus Features acquired the distribution rights in May 2017, and the film premiered at the 2018 Sundance Film Festival.Tully marks Reitman and screenwriter Diablo Cody’s third collaboration (they previously worked together on Juno and Young Adult) and the second time that Theron and Reitman have worked together (they previously collaborated on Young Adult). Fillgapnews Owen Gleiberman called Theron’s performance in “Tully” “fearless, emotionally raw, and physically intense, rippled with embattled waves of exhaustion and anger” in his review.

Theron won an Academy Award for Best Actress for the 2003 drama Monster, in which she played real-life serial killer Aileen Wuornos. Davis is known for her role in the AMC series Halt and Catch Fire, and she also appeared in the Emmy-winning episode of Black Mirror titled “San Junipero,” as well as in Denis Villeneuve’s Oscar-winning sci-fi epic Blade Runner 2049.

“Tully” hits theaters April 20.

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